Tuesday, February 16, 2016

Develop a 3D printer capable of producing human tissue – Daily Day

develop a 3D printer capable of producing human tissue

develop a 3D printer capable of producing human tissue

Scientists in the US have successfully implanted in animals living tissue structures made of a “sophisticated and improved” 3D printer, a study released today by the British magazine “Nature”.

This research, developed by the “Wake Forest Baptist Medical Center” in North Carolina, represents a breakthrough for regenerative medicine, it suggests that these structures could be implemented in the future in patients, surpassing ” several technical barriers “that hinder currently stand its leaders in a statement.

Experts printed “stable” and after implanting in rodents, matured into functional tissue, while they developed a system of blood vessels, cartilage, bone and muscle structures.

Although the new printed structures are not yet ready to be implanted in patients, remember, the first results of the study suggest that they have “the size, strength and stop functionality suitable to be used in humans.”

“This new printer tissues and organs is an important step in our goal to manufacture replacement tissue for patients progress,” says Anthony Atala, director of the Institute for Regenerative Medicine at Wake Forest (WFIRM, its acronym in English).

According to the expert, the “bioprinter 3D” can be made “stable human scale of any shape and size tissue,” allowing “print living tissue and organ structures for surgical implantation.”

For this work, the WFIRM has been funded by the Institute for Regenerative Medicine of the US military, which aims to apply this technology in soldiers wounded in combat, given the shortage of donor tissue for implants.

The accuracy of this new 3D printer means that in the near future, could faithfully replicate more complex tissues and organs of the human body.

Currently, researchers recall, current printers, whether injection laser or extrusion, can not reproduce structures having the necessary size or strength to be implanted in the body.

The so-called Integrated Print System Tissue and Organ (ITOP), developed by the WFIRM during the last ten years, has overcome these limitations, held Atala.

The ITOP so much as biodegradable plastics to create the “form” of tissue and water-based gels holding cells.

In addition, the 3D machine manufactures a strong temporal external structure, which prevents cell damage occurring during the printing process.

Another of the challenges of tissue engineering is to make the implanted structures live long enough to be integrated into the body.

In this regard, experts optimized the one hand, the “ink” of water based holding cells to improve their “health” and promote their growth, while printed a network of ” microchannels “structures.

These channels point, allow nutrients and oxygen present in the human body are integrated in those structures, keep alive and develop a system of blood vessels.

Research earlier showed that cells survive only when implanted tissue structures have not been able to develop blood vessels have a size less than 200 microns (0.1778 mm).

Atala and colleagues succeeded in manufacturing a ear of a size suitable for babies of 1.5 inches (38.1 millimeters) can survive and show signs of vascularization one two months after being implanted.

“Our results indicate that the use a “biotinta ‘combined, with the development of’ micro ‘, creates the right environment to keep cells alive and to encourage their growth and tissues,” says the researcher.

Another feature of the ITOP is its ability to process data from scans and MRIs and “make tissue to measure” for each patient.

LikeTweet

No comments:

Post a Comment