Identified neurotransmitter that regulates cocaine in mice – EntornoInteligente

Identify neurotransmitter that regulates cocaine in mice / Union Radio / “They feel before the stimulant effects of the drug, more easily develop an ‘addiction’ and are more susceptible to ‘relapse’ after a period of” abstinence “, he said today in a statement the French National Agency for Research Scientific (CNRS). The agent pointed out by researchers from the Institute of Biology at Paris-Seine and the University Institute of Mental Health Douglas McGill University in Montreal is glutamate, which acts on the brain’s reward system. “During drug use, increases the amount of dopamine in the brain structures forming the reward circuit. The intensity and speed of the release of dopamine underlie the process leading to the development of addiction,” sums up CNRS. It was known that in the process of cholinergic neurons of the nucleus accumbens of the brain responsible for regulating the supply of dopamine, through acetylcholine, responsible for releasing the substance involved. “Contrary to what we thought until now scientists is not only acetylcholine which regulates the release of dopamine, but the balance between this and glutamate,” the CNRS.

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