Madrid (Europa Press). – Two-time winner of two Nobel Prizes in Chemistry , Frederick Sanger , died Wednesday, at age 95, according has informed the foundation that bears his name through Twitter.
biochemist is considered one of the fathers of genomics, as his work helped decode the human genome. This is the only Brit to have won the prestigious award twice and the fourth in the story after Marie Curie, Linus Pauling and John Bardeen.
first won in 1958 for his work on the structure of proteins in plants and animals. During his research, Sanger determined the amino acid sequence of insulin and, in doing so, demonstrated that proteins have specific structures. The scientist called these patterns ‘fingerprint’ that can be used to identify each protein.
second Swedish Academy recognition came in 1980, after developing the DNA sequencing method, also known as the Sanger method.
Two years later
used this technique to sequence the F-X174 bacteriophage, the first body covering the genome completely sequenced. Also, did this work manually, without the help of automation. This work was fundamental basis for such ambitious projects as the Human Genome Project.
Sanger was born in Gloucestershire in 1918. He was educated at Bryanston School and later earned a bachelor’s degree in Natural Sciences at St John’s College, Cambridge. Originally thought of studying medicine, but became interested in biochemistry because of some of the best biochemical time were in Cambridge at the time. Eventually he earned his doctorate in 1943.
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