The Hudsucker Proxy Windows – Los Andes (Argentina)

Dio surprise, not so much for performance or news of your new system … if not by name.

 The next version of Microsoft’s operating system will be Windows 10 because the company will skip that version 9 would have been to emphasize the progress we are making towards a centered universe and mobile internet services .

 The current version, Windows 8, has been criticized for forcing radical changes in user behavior. Microsoft will restore some of the more traditional ways and promises that will be familiar to Windows 10 clients, regardless of which version of Windows you are using today.

 For example, the Start menu in Windows 10 appears similar to Windows 7, but the grids that will open on the right will look like those of Windows 8.

 Joe Belfiore, a Microsoft executive who oversees the design and development of Windows, said version 10 “offer the fa

miliaridad of Windows 7 with some of the benefits that exist in Windows 8″ to help users to make the transition.

 Microsoft yesterday offered a glimpse of the new version at an event in San Francisco for business customers.

 Although the new system will not be formally distributed until next year, analysts believe that its success will be crucial for Microsoft and its new CEO Satya Nadella.

 The new system represents an attempt to reverse in part the radical redesign that alienated many users when Windows 8 was introduced two years ago, but not completely away from the goal of bridging the gap between laptops and mobile devices: still has functions tactile, and aims to create a familiar experience for users who switch between desktops, tablets and multipurpose phones.

 The executive Terry Myerson said that Windows 10 will be “a whole new generation” that will work with a variety of devices, from phones to game consoles.

Team

 According to Microsoft, Windows 10 will be a “collaborative” operating system.

 To that end today launched the Insider Program and Windows users who sign up can download a technical preview to work on laptops and desktops.

 All other devices will have to wait.

 Apparently, and although they have not given many details on how will this program will have polls and forums available to insiders, where Microsoft engineers themselves are quite active.

 In fact, they have acknowledged that they do not know how well organized but “will learn” on the road.

 Windows 10 is still far from being completed and is expected to hit the consumer market in mid-2015

 In the Build event where Microsoft traditionally meets with developers, will present this operating system in detail.

 Regarding price or the rumor that the update would be free, as was said a few days ago, have not been pronounced.

New

Intended This major upgrade is simply to integrate once and the desktop environment with the Modern UI. Bringing together the best of Windows 7 with 8 attempts at modernization.

 Still argue that his new philosophy of “One”, a shop, an OS, a cloud, and the convergence of all its products.

 The Start Menu of Windows 10 has been completely overhauled to make it easier to use.

 Bar Charms (lateral) has not disappeared, but still, the search system has been improved and integrated to the Start Menu or Toolbar, if you will.

So Windows 10, the future of Microsoft – ABC.es

A. F. abc_tecnologia / Madrid

Day 1/10/2014 – 2:51 a.m.

microsoft

The start menu returns

microsoft

This is the virtual desktops

microsoft

The multi

microsoft

Taskbar

A bug in iOS 8 deletes saved in iCloud content – ABC.es

abc technology abc_tecnologia / Madrid

Day 30/09/2014 – 3:16 p.m.

efe content

A person shows an iPhone iOS 6 8

A light on the surface of Mars? – ElEconomista.es

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Note to users: 9.0 ( 1 votes)

Gradually keep coming curious images from Mars thanks to the work of NASA’s Curiosity rover, which is more than two years traveling the surface of the red planet in search of more data that we provide a more specific conomiento the same .

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The surprising finding in one of his latest snapshots has been a rock with a shape very similar to one of the lights to be found on any street in any city.

The discovery in question was made by a British journalist, director of a specialized program on YouTube, according to the newspaper points out Daily Mail .

Another finding was that of a rock with an almost perfect spherical shape resting on a flat rock and that it could be a hard solid mass formed by the accumulation of matter, although its size is not as big as it looks in pictures

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Smack: Facebook makes user data in a new … – Ideal Digital

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Microsoft today unveiled Windows 9 after the warm reception of Windows 8 – Five Days

The software giant Microsoft plans to unveil at 19:00 (Spanish local time) your new Windows 9 will be the previous version of the popular operating system, because it is expected that the final release will not take place until the spring of 2015. Although the Redmond company has not made public how the product will be some seepage collected by Gizmodo.es note that Windows 9 will be, in many respects, a return to origins, as “far as Windows 8 to blur the lines between traditional desktop systems and mobile operating systems, the new version of Windows delve into the more traditional desktop interface, “explains this technological web.

Microsoft knows the challenge ahead, because according to the data published by StatCounter on the market for operating systems for desktop and laptop Windows XP is still present in 14.80% of the teams. At the head is still Windows 7, which continues to rise. In August, this version of Windows had a 61.94% share compared to 62.52% stake in July. In contrast, Windows 8 suffered a slight decline in the same period, from 10.34% to 10.04%.

PC makers expect Windows 9 becomes a lever that boost sales of computers, which are several years suffering from the crisis and the pull of the tablets.

free for certain users

Microsoft Indonesia president Andreas Diantoro, said that Windows 9 will be free for users of Windows 8, Europa Press reported. Also this summer it was leaked that the new version of Windows would be free for users with older operating systems such as Windows 7 and Windows XP. A decision that would ensure mass migrations.

According to the German publication Winfuture, Windows 9 will identify the type of device (touch or non-touch) which is installed software to customize their interface accordingly, and will have a selection system based virtual desktops on a carousel. Something similar to OSX or Ubuntu works, pointing Gizmodo.es.

Plankton live on the outside of the ISS and bacteria that resist travel … – Trends 21

The last August, Russian space officials on board the International Space Station (ISS) said in comments reported by the Russian news agency ITAR-TASS have found traces of marine plankton and other living organisms on the outside of the station.

According to them, the plankton was not there at the time of the launching of the International Space Station, launched in November 1998, when the Russian Proton rocket placed in orbit the largest Russian module Zarya, the main model and designed to provide the space station and initial energy propulsion. Subsequently, new modules were added to this structure, which may have been made permanent human presence in space for the first time in history.

As microorganisms found had not been put there by humans, how arrived at the ISS? According astronauts ventured then, surely drafts from Earth.

The NASA spokesman, Dan Hout said about it, also in August that “We have not had access to any official report from our colleagues Roscosmos (the Russian space agency) about the discovery of plankton on the outside of the ISS “, picked Space.com.

Now the story returns to the media highlighting how amazing the fact that microbes can survive in the vacuum of space, despite temperatures ice cream makers, lack of oxygen and cosmic radiation prevailing there.

Findings made itself

Whether or not marine plankton dwelling on the outside of the ISS, as had been demonstrated by other means, that certain forms of life could survive a while-at least under the conditions of space.

In 2012, three experiments performed by scientists at NASA on the ISS itself, to determine whether living organisms could reach Mars in future human spacecraft revealed that some microbes themselves have this capability.

For example, spore-forming bacterium Bacillus pumilus SAFR-032 survived for 18 months in the European Technology Exposure Facility (EuTEF), a load mounted on the outside of the International Space Station which allows to exhibit materials directly to the harsh space environment.

A second experiment with spores of the same bacteria and other spore-forming bacteria, submitted for a year and a half of space vacuum conditions and a simulated Martian atmosphere, revealed that all of them would survive a trip in a spacecraft to Mars, if they remain protected against solar radiation.

The third experiment, which consisted of placing year and a half in space rocks cellular organisms specially adapted to extreme environmental conditions of some terrestrial habitats, also found that these agencies would also resist in space.

Life Beyond the ISS?

In addition, to date, scientists have found what appear to be traces of life forms in Martian meteorites or in the stratosphere; and complex organic substances in outer space.

In this regard, the latter finding has recently produced: A team of researchers from Cornell University (USA) and the Max Planck Institute for Radio Astronomy and the University of Cologne (two centers in Germany ) just made public the discovery in interstellar space in an unusual organic molecule, it has a (own of the molecules necessary for life, such as amino acids), branched structure rather than linear, as usually found in the cosmos. This discovery was made at 27,000 light years away thanks to the ALMA Observatory, the world’s most sensitive radiotelecopio.

All these findings seem to support the theory of panspermia, which argues that the essential elements for life were formed in the early stages of evolution of the universe expanding this. According to this hypothesis, life would come to Earth thanks to the impacts suffered by our planet at an early stage of their training.

Scientists puzzled by a mysterious glow seen in the m – La Vanguardia

Madrid. (EP) .- spacecraft Cassini NASA is following the evolution of a mysterious feature the sea of ​​oil Ligeia Mare in the Moon Saturn Titan . Through the images captured by the probe, scientists have found that the appearance of this large body of water, one of the largest satellite, has changed in recent years.

In one of the Cassini observations in July 2013, the mission team saw a feature in the photographs, shone on the dark background of the liquid sea. It was the first time that this anomaly, which did not appear in the data from previous flybys looked.

Scientists were puzzled to find this shine and discover that, months later, it had vanished. This led to some team members to suggest it might have been a transient feature. But during the flyby on August 21, 2014, the property was again visible. That is, his appearance had changed in the past 11 months since he was last seen.

NASA has already ruled that this event is the result of a defect in the Cassini radar and it is therefore evaporation in the sea as the coast of Ligeia Mare has not changed significantly. On the contrary, it has been suggested that this feature might be the result of surface waves, rising bubbles, a floating solid or suspended just below the surface, or perhaps “something more exotic.”

Researchers suspect that the appearance of this feature could be related to the change of seasons in Titan . Monitoring such changes is an important current goal Cassini extended mission.

“Science loves mysteries, and this enigmatic feature, we have a thrilling example of ongoing changes on Titan” he pointed out one of the leaders of the mission, Stephen Wall. “We hope that we will be able to continue watching the changes unfold and get an idea about what is happening in that alien sea,” he concluded.

Facebook provides data users a platform to … – The New Spain

EFE / San Francisco The giant social networking Facebook today brought to market a new platform that facilitates data its users to advertisers so they can place their advertising more effectively in third portals.

The Atlas platform collects data of Facebook and used in external websites, so if for example, a user clicks the “ Like ” of the social network on a page of sports shoes, you may thereafter will appear ads for similar products on other websites .

With the data collected through Facebook A history of the tastes and interests of each user to allow advertisers to better identify potential buyers is drawn .

Atlas Facebook bought last year to Microsoft for $ 100 million and after redesign it completely, has finally released Monday.

to Facebook now selling advertising space on the network and used cookies calls (“cookies”) to track the tastes of users during a boat other websites and thus lead them ads according to their preferences.

new methodology is intended, in principle, to improve the advertising effectiveness , because cookies present some inaccuracies and do not track the browsing on mobile devices, which Atlas, through Facebook, it does .

Facebook deals with this movement a little closer to its major competitor in Internet advertising, Google , who continues beating him by a wide margin.

In the fiscal second quarter of this year, Google introduced advertising benefits worth 14.360 billion, while Facebook received over the same period 2,680 million, ie almost five times less.

Uncover remains of living plankton outside the station … – The Courier

The occupants of the International Space Station (ISS) have come up with new evidence confirms the theory that life can exist without oxygen, under the scrutiny of cosmic radiation and the vacuum dominates beyond the atmosphere Earth. And Russian officials have reported that the crew of the ISS located during a routine hike in August, plankton and other organisms alive in the outer shell of the facility.

These experts argue that these tiny life forms could be there before launch. That is, they could have flown transported by air currents.

These experts argue that these tiny life forms could be there before launch. That is, they could have flown there transported by air currents

The crew used cloths to polish the surface of the windows of the Russian segment of the orbiter, an activity that takes place from time to time precisely for changes space that occurs on the ISS.

The Most

“The results of the experiment are quite unique,” said the head of the Russian orbital mission, Vladimir Soloviev. The expert indicated that is still being worked on to know the origin of these microscopic particles and how they came to the surface of the device.

In the oceans

As the type of plankton found, has indicated that it is equal to that can be found on the surface of the oceans during the development stage. In this sense, Roscosmos said that “not typical” of Baikonur, where releases are made.

Meanwhile, NASA thinks the idea of ​​the updrafts of the Earth as the cause the presence of plankton in space is completely “ridiculous.” In addition, Americans say they have not been officially informed of this event by Russia. “As far as we are concerned, we have not seen or heard the official reports of our colleagues Roscosmos about plankton found”, explained to Space.com NASA spokesman Dan Huot.

Please note: Microsoft presents a new version of Windows … – Ideal Digital

Technology: The project, known as Thresold (Threshold) within the company’s software and Windows 9 on the outside, is likely to receive a completely new name or simply call Windows, analysts, before full release in 2015, as reported

Confirmed:. Users of Windows 8 are in luck. Now, thanks to the initiative of Microsoft, all they can upgrade the operating system by installing the Windows 9 for free.

This news was finally confirmed by the president of Microsoft Indonesia, Andreas Diantoro.

The Most

In a recent interview, Diantoro has confirmed that Windows 8 users will not have to pay anything to upgrade to Windows 9, once the implementation of the operating system be released.

Last summer, the rumor that Windows 9x would be free for users of older Windows, including Windows XP and Windows 7 was extended.

However, only the Windows 8 users can install this system, once the Windows 9 to be presented, from Tuesday 30 September.

While the features of this system are disclosed, still there is speculation the name that will finally take because France has hinted that Microsoft Windows 9 will be the final one.

Currently, Web TH Microsoft Windows has called the new tab on the Technical Preview that now appears in the section on operating systems, with Windows 7 and Windows 8 Given these letters, many point to “Windows Threshold” as the final name.

Nuclear fusion will solve the greenhouse effect, says Hawking – Pulso de San Luis

Santa Cruz de Tenerife.- Physicist Stephen Hawking said today that the technological breakthrough that would like to see in the next hundred years is nuclear fusion because it the planet’s energy problem would be solved and we would save the greenhouse gases. /> Hawking was responding one of the questions chosen by Starmus Festival, which since Monday has joined the Atlantic island of Tenerife science , music and art and was closed today with a lecture by British physicist. /> Hawking, that when you got to choose between traveling to the Big Bang or the future chose the second choice because, he said, you know what happened in the past, said that may have Earth-like planets but does not believe in the existence of UFOs. /> The physicist said that the more you discover, the more mysteries there, so do not think that once the investigations are finished and explained that in his field, the physical fundamental and cosmology, not the implications of string theory are understood, and did not even know if it is correct. /> added that no one has thought of the nature of matter and dark energy, if particles, fields, or modifications of the theory. /> Hawking also joked about black holes, of which he said are not as black as the paint and can leave of them, both outwardly as possibly in another universe, so if someone feels that it is in a black hole should not give up because no output. /> During his talk on black holes Stephen Hawking said that they have an edge, called the event horizon, beyond which no return and falls for him. /> explained that in application of quantum mechanics, if a particle falls into a black hole or your partner may not fall, and in the second case is what gives rise to the radiation emitted by black holes. /> The antiparticle falling to black hole can be considered as a particle that is traveling to the past, Hawking said. /> He added that when a particle falls into a black hole information could be lost, which would be bad because during the last two hundred years we have believed in scientific determinism. /> For Stephen Hawking, if determinism fails with black holes may fail on other issues. /> indicated that from the outside of a black hole can not be sure whether or not there, which is always the possibility that does not exist. /> But asked if possible falling into a black hole and exit at another universe, and replied that in that case should have a hall to the other universe, but could not return.

Windows 9: what is known so far … next software – ABC.es

abc technology abc_tecnologia / Madrid

Day 30/09/2014 – 1:59 a.m.

ComputerBase

One of the filtered images

Windows 9 also will be free for users of Windows 8 – ABC.es

ep / Madrid

Day 29/09/2014 – 11:56 a.m.

microsoft China

Picture posted on Weibo account of Microsoft China

Found a ‘traffic light’ on Mars – Reuters

Barcelona. (Editorial) .- The Curiosity rover , which is more than two years analyzing the surface of Mars , no stops sending pictures spectacular of the red planet. One of the latest is at least curious. It is a rock with a striking resemblance to the traffic lights on Earth.

This curious figure was spotted by a journalist from Bristol (United Kingdom) driving ArtAlienTV YouTube channel. “I saw this and thought, ‘Wait, seems a bit odd,’” says Joe White to Daily Mail . “I think it looks like a traffic light,” he adds.

It is clear that the finding is coincidental. Are just rocks that can generate overlapping in the collective imagination the form of a traffic light. But it is indicative of the many surprises that can bring us the red planet.

There is a second finding on the surface of Mars that has attracted attention. It is a ball almost perfectly spherical shape which rests on a flat rock. According to NASA scientists, is not as great as it seems-that only about two-fifths of a inch-and is more likely to be a “specificity”, ie, a hard solid mass formed by the accumulation of matter .

The 60th anniversary of CERN, the largest particle physics laboratory … – Reuters

RTVE.es

CERN, the European Organization for Nuclear Research located in Geneva (Switzerland), celebrates its 60th anniversary along with delegations from 35 countries Monday.

This is the particle physics laboratory The world in which largest work of nearly 100 nationalities researchers .

Milestones CERN

Among the great achievements of CERN, emphasizes the idea that gave birth to the web emerged within its walls in 1989, when Tim Berners-Lee proposed to his boss to create a system that would allow the various departments of the center share information using a format that produced Standard under which no matter what type of computer used.

More recently, the July 4, 2012, a team of scientists at CERN announced the discovery of a subatomic particle could be the Higgs boson , a particle considered key to understanding the universe.

experiments conducted at CERN facilities , specifically in CMS (a detector in the Large Hadron Collider, LHC) and ATLAS (other experiments), sought to confirm the theories proposed in 1964 by Peter Higgs (UK), and François Englert (Belgium) and Robert Brout (EE .S.).

Very close to it after new evidence in 2013 that indicated that the new particle is looking more and more like a Higgs boson, the Higgs Englert and scientists received the Nobel Prize in Physics that year. A few months earlier, both physical and CERN itself received the Prince of Asturias Prize for Scientific Research for his research.

Birth after World War II

The CERN He was born on September 29, 1954, although its origins date back to the 1940s a small group of visionary scientists and public administrators on both sides of the Atlantic, identified basic research as a vehicle to rebuild the devastated continent .

At CERN speak the universal language of science

“For six decades, CERN has been a place where people can work together, regardless of culture and nationality. formed a bridge between cultures to speak a universal language, that language is science, “said CERN Director General Rolf Heuer, as recorded by the organism in a note.

In 1954, 12 member states signed the founding act that led the agency could start working. In later years more countries have joined the CERN, including Spain , and currently has 21 members and more than 10,000 users worldwide.

“With time, CERN has become worldwide leader in laboratory particle physics , always focused on achieving excellence, “noted the President of the CERN Council, Agnieszka Zalewska.

Thanks to the instruments made by the body, such as accelerators of ever more powerful particle and research findings, CERN has been able to explore new frontiers of energy.

Some of his discoveries have improved Greatly understanding of the fundamental laws of nature and allowed the advancing technologies.

CERN 60 years colliding particles – Online

The CERN, the European Organization for Nuclear Research, held on Monday 60 springs at an event attended by official delegations from 35 countries, including Spanish , who, on entry, have I left their signature for posterity on an electronic tablet located in the photocall .

CERN is currently laboratory for particle physics in the world , and a great example of international collaboration, it brings together over 10,000 scientists in almost 100 nationalities. Emerged on September 29, 1954 “to build a center of excellence in science, but also, somehow, restart contacts between scientists’ and unite nations says the president of the CERN Council, Agnieszka Zalewska. Thus, the theme of this anniversary is ’60 Years of Science for Peace ‘, recalling the agreement that allowed the scientific research exclusively for peaceful purposes .

‘Create a bridge between cultures that speak one universal language, and that language is science. “

“During these six decades, CERN has always been a place where people can work together, regardless of culture and nationality. create a bridge between cultures that speak one universal language, and that language is science “, said the director general of the Organization, Rolf Heuer, during his opening speech at the ceremony, said that the philosophy of this institution should serve as an example in a world in which” if you open a newspaper, any day, any time, anywhere, you will find human suffering. ” So, Heuer said that CERN, “cultures can coexist and make a difference” .

The revolution of Physics

The CERN is dedicated to fundamental physics, focused on discovering what is the universe made of and how it works . Since the creation of this organization, the picture of fundamental physics has changed dramatically. At the time, the knowledge of matter at smaller scales was limited to the nucleus of the atom . In the 60s, particle physicists were able to advance in this field to develop the Standard Model of Particle Physics and improving the knowledge of the Universe and its early .

The CERN is to discover what the universe is made and how it works.

bigger and more powerful accelerators have allowed researchers to explore new energy frontiers. Among the major discoveries at CERN are the carrier particles of the weak force , winner of the Nobel in 1984; the creation of the World Wide Web by Tim Berners-Lee in 1989, the development of a revolutionary particle detector by George Charpak, Nobel laureate also in 1992; and the discovery of the Higgs boson in 2012, he has been able to prove the Brout-Englert mechanism-Higgs and allowed the Nobel Prize Peter Higgs and François Englert in 2013.

The CERN handles the main particle accelerator in the world, the Large Hadron Collider (LHC). With its reboot next to a new record of energy, CERN will continue year looking for answers to some of the fundamental questions of the Universe .

Curing Cancer antimatter

Great minds at CERN are used not only for fundamental physics but there is space for the medication . The Antiproton Cell Experiment (ACE) was launched in 2003 and aims to fully assess the effectiveness of the antimatter as cancer therapy .

Recreating an antiproton beam against a tumor cell. <= span itemprop" author "class =" author "> CERN

To date, the particle beam therapy has been used mainly protons to destroy cancer cells. Unfortunately, although the beam destroys cancer also damages healthy tissue in repeated treatments. However, the ACE experiment is testing the idea of ​​ use antiprotons as an alternative treatment , by direct comparison of the effectiveness of cell irradiation using protons and antiprotons.

When matter (tumor cells) and antimatter (antiprotons) meet, they destroy each other, transform mass into energy. So, the released energy is projected into fragments of cancer cells adjacent, which in turn should also be destroyed.

According to the researchers at CERN, ACE is an excellent example of how research in particle physics can provide innovative solutions with potential health benefits . However, the validation process for any new medical treatment is long. Even if all goes well, it could still take a decade for the first clinical application to appear.

Spain at CERN

Spain is a member of CERN since 1983 and is ranked number five on taxpayers behind Germany, France, UK and Italy. Furthermore, according to the Ministry of I + D + i, “other funds were available to finance the activities of the Spanish research groups participating in experiments at CERN, including the LHC ISOLDE nTOF O”.

So, over 70 Spanish companies involved in construction, and maintenance of LHC, where currently working near 200 Spanish through ten research centers. This participation encourages the Secretary of State through the National Programme for Particle Physics and the National Center for Particle Physics, Astroparticle and Nuclear (CPAN) Consolider-Ingenio 2010 project managed by the CSIC.

Secretary of State for R + D + i, Carmen Vela, who has captained the Spanish delegation at the event, noted the importance for Spain “participating in an organization that is at the forefront of world science that enables researchers and Spanish technicians do big science “.

Apple removed the option to go back to iOS 7 – Radio Santa Fe

Apple removed the option allowing users to reinstall iOS 7 on their devices. The company had kept this possibility in the early days of iOS 8, but eventually withdrew the option.

Apple has faced various problems this week . The company has seen as the first iOS update 8 was a failure and had to recommend to many users they returned to the first version of its new system. At that time, also allowed back to iOS 7, an option that some people have used to find a more fluid performance on their devices.

After these problems, finally iOS 8.0.2 was Apple’s solution , which ended with incidents on users iPhone 6 Once launched and tested that version of the operating system, Apple has decided to withdraw the permissions and tools to return to iOS. 7

The company would considered to be no longer necessary to have that possibility since iOS itself is 8 now stable and is the best choice for compatible equipment. Thus, Apple no longer offers the possibility to return to an older version of iOS, as confirmed in MacWorld.

This is a move that makes sense given that Apple, like other companies, always want their customers always have the latest versions of software available. The main reason is security, since most modern versions often have patches and fixes.

In addition, by having the latest versions of software users can take advantage of new features and services introduced, factors that are also of interest for Apple and other companies responsible for software.

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Stem cells can be traced through its … – VLC News

A team from the National Cancer Research Centre (CNIO) has discovered a luminous property of tumor stem cells that help trace the source of resistance to chemotherapy and develop treatments against these cells. According to the study, published in the journal Nature Methods, these cells accumulate in your body riboflavin or vitamin B2, a pigment that emits green fluorescence as a result of their accumulation in intracellular vesicles.

The cancer stem cells have been identified in recent years as responsible for the origin of cancer and resistance to conventional chemotherapies. Now, a team of National Cancer Research Centre (CNIO) found that these cells have a property that allows light track them easily.

The reason for this peculiarity is that these cells accumulate in your body or riboflavin Vitamin B2, a pigment that emits green fluorescence as a result of their accumulation in intracellular vesicles.

“The discovery of this new marker is a breakthrough because it identifies tumor stem cells are more invasive and chemoresistant. The autofluorescence of these cells allow tracking them in an easy, simple and cheap way, and to study the origin of the chemoresistance of tumors, “says Irene Miranda, one of the authors of the study published in the latest issue of the magazine Nature Methods.

This discovery could boost personalized medicine of the future and the development of more effective cancer treatments. “From now on autofluorescence can isolate cells from a biopsy and test its sensitivity to a panel of experimental or marketed drugs and” say Sainz and Heeschen, other authors.

Only between 1% and 2% of the entire tumor mass is made up of tumor stem cells. Such a small percentage hinders their isolation and analysis, and the study of the origin of drug resistance.

“The discovery of the new marker will allow identify tumor stem cells quickly, easily and cheaply “, scientists

” Normally we only see the leaves of the tree representing tumors and can not make out the roots, which are the Authentic responsible for their progression and growth, “Miranda said.

Drug Development

The discovery has been made in several tumor types, including samples from patients with pancreatic, liver, colon and lung cancer, raises a question: Why tumor stem cells accumulate vitamin B2

The researchers show in the article that is due to an increase in? ABCG2 protein, responsible for the transport of vitamin inward conferring intracellular vesicles brightness cells. The reason for this phenomenon is yet to be determined.

Despite the unknowns about its nature, the researchers emphasize that this discovery will accelerate the identification of new drugs or combinations thereof that are capable of removing stem cells cancer in a particular patient

References:.

Irene Miranda-Lorenzo et al . “Intracellular autofluorescence: a biomarker for epithelial cancer stem cells.” Nature Methods (2014). doi: 10.1038 / nmeth.3112